APRT Antibody
Product Specifications
Background
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP) . It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
353
Swiss Prot
P07741
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 20kDa
Fragment
IgG
Symbol
APRT
Positive Control 2
22Rv1
Positive Control 3
THP-1
Positive Control 4
A-549
Positive Control 5
K-562
Positive Control 6
HeLa
NCBI Official Name
Adenine phosphoribosyltransferase
NCBI Organism
Homo sapiens
Other Product Names
APRT, AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961, APRTD
Tested Applications
WB, IF
Physical Properties
Liquid
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