MERTK Antibody
Product Specifications
Background
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .
NCBI Gene ID
10461
Swiss Prot
Q12866
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 840-999 of human MERTK (NP_006334.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 160kDa
Fragment
IgG
Symbol
MERTK
Positive Control 2
Mouse liver
Positive Control 3
Mouse kidney
Positive Control 4
Mouse lung
Positive Control 5
Mouse spleen
Positive Control 6
Rat liver
NCBI Official Name
C-mer proto-oncogene tyrosine kinase
NCBI Organism
Homo sapiens
Other Product Names
MERTK, c-mer proto-oncogene tyrosine kinase , MER, MGC133349, c-mer, MER receptor tyrosine kinase, STK kinase
Tested Applications
WB, IF
Physical Properties
Liquid
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