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MERTK Antibody

Product Specifications

Background

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

NCBI Gene ID

10461

Swiss Prot

Q12866

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 840-999 of human MERTK (NP_006334.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

22Rv1

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-665

Calculated Molecular Weight

Observed: 160kDa

Fragment

IgG

Symbol

MERTK

Positive Control 2

Mouse liver

Positive Control 3

Mouse kidney

Positive Control 4

Mouse lung

Positive Control 5

Mouse spleen

Positive Control 6

Rat liver

NCBI Official Name

C-mer proto-oncogene tyrosine kinase

NCBI Organism

Homo sapiens

Other Product Names

MERTK, c-mer proto-oncogene tyrosine kinase , MER, MGC133349, c-mer, MER receptor tyrosine kinase, STK kinase

Tested Applications

WB, IF

Physical Properties

Liquid

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