GARS Antibody
Product Specifications
Background
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha) 2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2617
Swiss Prot
P41250
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 60-370 of human GARS (NP_002038.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-658
Calculated Molecular Weight
Observed: 83kDa
Fragment
IgG
Symbol
GARS
Positive Control 2
293T
Positive Control 3
U-87MG
Positive Control 4
Raji
Positive Control 5
M21
Positive Control 6
HT-29
NCBI Official Name
Glycyl-tRNA synthetase
NCBI Organism
Homo sapiens
Other Product Names
CMT2D, DSMAV, GlyRS, HMN5, SMAD1, glycine--tRNA ligase, AP-4-A synthetase, Charcot-Marie-Tooth neuropathy 2D, Charcot-Marie-Tooth neuropathy, neuronal type, D, ap4A synthetase, diadenosine tetraphosphate synthetase
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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