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RIP3 Antibody

Product Specifications

Background

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

NCBI Gene ID

11035

Swiss Prot

Q9Y572

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RIP3 (NP_006862.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Immunology, Innate Immunity, Signal Transduction

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-657

Calculated Molecular Weight

Observed: 45-70kDa

Fragment

IgG

Symbol

RIPK3

Positive Control 2

Mouse spleen

Positive Control 3

Mouse lung

Positive Control 4

Rat lung

NCBI Official Name

Receptor-interacting serine-threonine kinase 3

NCBI Organism

Homo sapiens

Other Product Names

RIPK3, RIP3, RIP3 beta, RIP3 gamma

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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