RIP3 Antibody
Product Specifications
Background
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
NCBI Gene ID
11035
Swiss Prot
Q9Y572
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RIP3 (NP_006862.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Immunology, Innate Immunity, Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45-70kDa
Fragment
IgG
Symbol
RIPK3
Positive Control 2
Mouse spleen
Positive Control 3
Mouse lung
Positive Control 4
Rat lung
NCBI Official Name
Receptor-interacting serine-threonine kinase 3
NCBI Organism
Homo sapiens
Other Product Names
RIPK3, RIP3, RIP3 beta, RIP3 gamma
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Frequently Asked Questions
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