CHMP2B Antibody
Product Specifications
Background
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
NCBI Gene ID
25978
Swiss Prot
Q9UQN3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human CHMP2B (NP_054762.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Autophagy, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-639
Calculated Molecular Weight
Observed: 28kDa
Fragment
IgG
Symbol
CHMP2B
Positive Control 2
BT-474
Positive Control 3
22Rv1
Positive Control 4
Lovo
Positive Control 5
A-549
Positive Control 6
Mouse lung
NCBI Official Name
Charged multivesicular body protein 2B
NCBI Organism
Homo sapiens
Other Product Names
ALS17, CHMP2.5, DMT1, VPS2-2, VPS2B, charged multivesicular body protein 2b, VPS2 homolog B, chromatin modifying protein 2B, vacuolar protein-sorting-associated protein 2-2
Tested Applications
WB, IHC
Physical Properties
Liquid
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