PVRL2 Antibody

Product Specifications

Background

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

NCBI Gene ID

5819

Swiss Prot

Q92692

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human PVRL2 (NP_002847.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

Affinity purification

Positive Control

MCF-7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 72kDa

Fragment

IgG

Symbol

PVRL2

Positive Control 2

SW620

Positive Control 3

A-549

Positive Control 4

SKOV3

NCBI Official Name

Nectin cell adhesion molecule 2

NCBI Organism

Homo sapiens

Other Product Names

CD112, HVEB, PRR2, PVRL2, PVRR2, nectin-2, herpesvirus entry protein B, poliovirus receptor-like 2, poliovirus receptor-related 2 (herpesvirus entry mediator B)