GHRH Antibody
Product Specifications
Background
This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
NCBI Gene ID
2691
Swiss Prot
P01286
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-107 of human GHRH (NP_001171660.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 15kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
GHRH
Positive Control 2
HL-60
Positive Control 3
U-937
Positive Control 4
Mouse liver
NCBI Official Name
Growth hormone releasing hormone
NCBI Organism
Homo sapiens
Other Product Names
GHRF, GRF, INN, somatoliberin, growth hormone releasing factor, sermorelin, somatocrinin, somatorelin
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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