RCAN1 Antibody
Product Specifications
Background
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
1827
Swiss Prot
P53805
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 60-245 of human RCAN1 (NP_004405.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 31kDa
Fragment
IgG
Symbol
RCAN1
Positive Control 2
SKOV3
Positive Control 3
U-87MG
NCBI Official Name
Regulator of calcineurin 1
NCBI Organism
Homo sapiens
Other Product Names
RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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