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RACGAP1 Antibody

Product Specifications

Background

This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.

NCBI Gene ID

29127

Swiss Prot

Q9H0H5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 353-632 of human RACGAP1 (NP_001119576.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Chemokines & Cytokines, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 82kDa

Fragment

IgG

Symbol

RACGAP1

Positive Control 2

K-562

Positive Control 3

Jurkat

NCBI Official Name

Rac GTPase activating protein 1

NCBI Organism

Homo sapiens

Other Product Names

RACGAP1, CYK4, ID-GAP, HsCYK-4, MgcRacGAP

Tested Applications

WB, IF

Physical Properties

Liquid

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