WWP1 Antibody
Product Specifications
Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.
NCBI Gene ID
11059
Swiss Prot
Q9H0M0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human WWP1 (NP_008944.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
PC-3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-555
Calculated Molecular Weight
Observed: 95kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
WWP1
NCBI Official Name
WW domain containing E3 ubiquitin protein ligase 1
NCBI Organism
Homo sapiens
Other Product Names
AIP5, Tiul1, hSDRP1, NEDD4-like E3 ubiquitin-protein ligase WWP1, HECT-type E3 ubiquitin transferase WWP1, Nedd-4-like ubiquitin-protein ligase, TGIF-interacting ubiquitin ligase 1, WW domain-containing protein 1, atrophin-1 interacting protein 5
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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