WWP1 Antibody

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.

AIP5, Tiul1, hSDRP1, NEDD4-like E3 ubiquitin-protein ligase WWP1, HECT-type E3 ubiquitin transferase WWP1, Nedd-4-like ubiquitin-protein ligase, TGIF-interacting ubiquitin ligase 1, WW domain-containing protein 1, atrophin-1 interacting protein 5