RRM2 Antibody
Product Specifications
Background
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
NCBI Gene ID
6241
Swiss Prot
P31350
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-389 of human RRM2 (NP_001025.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
MCF-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Symbol
RRM2
Positive Control 2
SW480
Positive Control 3
HeLa
Positive Control 4
Jurkat
Positive Control 5
Mouse thymus
NCBI Official Name
Ribonucleotide reductase M2
NCBI Organism
Homo sapiens
Other Product Names
RRM2, R2, RR2M, RR2
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
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