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RRM2 Antibody

Product Specifications

Background

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.

NCBI Gene ID

6241

Swiss Prot

P31350

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-389 of human RRM2 (NP_001025.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

MCF-7

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-553

Calculated Molecular Weight

Observed: 45kDa

Fragment

IgG

Symbol

RRM2

Positive Control 2

SW480

Positive Control 3

HeLa

Positive Control 4

Jurkat

Positive Control 5

Mouse thymus

NCBI Official Name

Ribonucleotide reductase M2

NCBI Organism

Homo sapiens

Other Product Names

RRM2, R2, RR2M, RR2

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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