SPTBN1 Antibody

Product Specifications

Background

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

6711

Swiss Prot

Q01082

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2100-2200 of human SPTBN1 (NP_003119.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 275kDa

Fragment

IgG

Applications Notes

WB: 1:1000 - 1:3000

Symbol

SPTBN1

Positive Control 2

HeLa

Positive Control 3

Jurkat

Positive Control 4

LO2

Positive Control 5

293T

Positive Control 6

Mouse brain

NCBI Official Name

Spectrin beta, non-erythrocytic 1

NCBI Organism

Homo sapiens

Other Product Names

ELF, HEL102, SPTB2, betaSpII, spectrin beta chain, non-erythrocytic 1, beta-G spectrin, beta-II spectrin, beta-fodrin, beta-spectrin 2, beta-spectrin II, beta-spectrin non-erythrocytic 1, embryonic liver beta-fodrin, epididymis luminal protein 102, fodrin beta chain, spectrin beta chain, brain 1, spectrin, non-erythroid beta chain 1