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SNX19 Antibody

Product Specifications

Background

Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles.

NCBI Gene ID

399979

Swiss Prot

Q92543

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SNX19 (NP_055573.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 108kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SNX19

Positive Control 2

Mouse testis

Positive Control 3

Rat brain

NCBI Official Name

Sorting nexin 19

NCBI Organism

Homo sapiens

Other Product Names

SNX19, sorting nexin 19, CHET8, DKFZp667I205, KIAA0254

Tested Applications

WB

Physical Properties

Liquid

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