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CDH23 Antibody

Product Specifications

Background

This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.

NCBI Gene ID

64072

Swiss Prot

Q9H251

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 40-270 of human CDH23 (NP_001165402.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-497

Calculated Molecular Weight

Observed: 52kDa

Fragment

IgG

Applications Notes

WB: 1:200 - 1:1000

Symbol

CDH23

Positive Control 2

B cells

Positive Control 3

Mouse liver

Positive Control 4

Mouse testis

Positive Control 5

Mouse heart

Positive Control 6

Mouse kidney

NCBI Official Name

Cadherin-related 23

NCBI Organism

Homo sapiens

Other Product Names

CDH23, cadherin-like 23, DFNB12, DKFZp434P2350, FLJ00233, FLJ36499, KIAA1774, KIAA1812, MGC102761, USH1D, USH1H, OTTHUMP00000044780, cadherin 23, cadherin related 23, cadherin-23, otocadherin, UNQ1894/PRO4340

Tested Applications

WB

Physical Properties

Liquid

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