MRM3 Antibody

Product Specifications

Background

Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G (1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

55178

Swiss Prot

Q9HC36

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-420 of human MRM3 (NP_060616.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 47kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

MRM3

Positive Control 2

HepG2

Positive Control 3

293T

NCBI Official Name

Mitochondrial rRNA methyltransferase 3

NCBI Organism

Homo sapiens

Other Product Names

RMTL1, RNMTL1, rRNA methyltransferase 3, mitochondrial, 16S rRNA (guanosine (1370) -2'-O) -methyltransferase, 16S rRNA [Gm1370] 2'-O-methyltransferase, RNA methyltransferase like 1, RNA methyltransferase-like protein 1, putative RNA methyltransferase