NANS Antibody
Product Specifications
Background
This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
NCBI Gene ID
54187
Swiss Prot
Q9NR45
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 260-359 of human NANS (NP_061819.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-466
Calculated Molecular Weight
Observed: 40kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
NANS
Positive Control 2
OVCAR3
Positive Control 3
A-431
NCBI Official Name
N-acetylneuraminate synthase
NCBI Organism
Homo sapiens
Other Product Names
HEL-S-10SAS, SEMDCG, SEMDG, sialic acid synthase, N-acetylneuraminate-9-phosphate synthase, N-acetylneuraminic acid phosphate synthase, N-acetylneuraminic acid synthase, epididymis secretory protein Li 10sialic acid phosphate synthase
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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