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HOOK1 Antibody

Product Specifications

Background

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.

NCBI Gene ID

51361

Swiss Prot

Q9UJC3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 489-728 of human HOOK1 (NP_056972.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

LO2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-454

Calculated Molecular Weight

Observed: 85-100kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

HOOK1

Positive Control 2

MCF7

Positive Control 3

22Rv1

Positive Control 4

Mouse liver

Positive Control 5

Mouse kidney

Positive Control 6

Mouse brain

NCBI Official Name

Protein Hook homolog 1

NCBI Organism

Homo sapiens

Other Product Names

Protein Hook homolog 1, h-hook1, hHK1, HOOK1

Tested Applications

WB

Physical Properties

Liquid

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