HOOK1 Antibody
Product Specifications
Background
This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.
NCBI Gene ID
51361
Swiss Prot
Q9UJC3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 489-728 of human HOOK1 (NP_056972.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 85-100kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
HOOK1
Positive Control 2
MCF7
Positive Control 3
22Rv1
Positive Control 4
Mouse liver
Positive Control 5
Mouse kidney
Positive Control 6
Mouse brain
NCBI Official Name
Protein Hook homolog 1
NCBI Organism
Homo sapiens
Other Product Names
Protein Hook homolog 1, h-hook1, hHK1, HOOK1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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