AFF4 Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31; q31q23) .
NCBI Gene ID
27125
Swiss Prot
Q9UHB7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human AFF4 (NP_055238.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Transcription
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 150kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
AFF4
Positive Control 2
HeLa
Positive Control 3
293T
Positive Control 4
LO2
Positive Control 5
MCF7
Positive Control 6
Mouse pancreas
NCBI Official Name
AF4/FMR2 family member 4
NCBI Organism
Homo sapiens
Other Product Names
AF5Q31, CHOPS, MCEF, AF4/FMR2 family member 4, ALL1-fused gene from chromosome 5q31 protein, major CDK9 elongation factor-associated protein
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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