ATXN10 Antibody
Product Specifications
Background
This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
NCBI Gene ID
25814
Swiss Prot
Q9UBB4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 346-475 of human ATXN10 (NP_037368.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ATXN10
Positive Control 2
SKOV3
Positive Control 3
LO2
Positive Control 4
HL-60
Positive Control 5
293T
Positive Control 6
Mouse heart
NCBI Official Name
Ataxin 10
NCBI Organism
Homo sapiens
Other Product Names
E46L, HUMEEP, SCA1ataxin-1brain protein E46 homolog, spinocerebellar ataxia type 10 protein
Tested Applications
WB
Physical Properties
Liquid
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