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CES3 Antibody

Product Specifications

Background

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.

NCBI Gene ID

23491

Swiss Prot

Q6UWW8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 269-568 of human CES3 (NP_001172106.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

LO2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 62kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CES3

Positive Control 2

HT-29

Positive Control 3

Mouse small intestine

Positive Control 4

Mouse large intestine

Positive Control 5

Rat liver

Positive Control 6

Rat small intestine

NCBI Official Name

Carboxylesterase 3

NCBI Organism

Homo sapiens

Other Product Names

ES31, carboxylesterase 3, carboxylesterase 3 (brain), esterase 31, liver carboxylesterase 31 homolog

Tested Applications

WB

Physical Properties

Liquid

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