SF3A3 Antibody
Product Specifications
Background
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
10946
Swiss Prot
Q12874
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 292-501 of human SF3A3 (NP_006793.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
B cells
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 59kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
SF3A3
Positive Control 2
A-549
Positive Control 3
HepG2
Positive Control 4
HeLa
Positive Control 5
HL-60
Positive Control 6
Mouse lung
NCBI Official Name
Splicing factor 3a, subunit 3, 60kDa
NCBI Organism
Homo sapiens
Other Product Names
SF3A3, PRP9, PRPF9, SAP61, SF3a60
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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