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SF3A3 Antibody

Product Specifications

Background

This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

10946

Swiss Prot

Q12874

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 292-501 of human SF3A3 (NP_006793.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

B cells

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 59kDa

Fragment

IgG

Applications Notes

WB: 1:200 - 1:2000

Symbol

SF3A3

Positive Control 2

A-549

Positive Control 3

HepG2

Positive Control 4

HeLa

Positive Control 5

HL-60

Positive Control 6

Mouse lung

NCBI Official Name

Splicing factor 3a, subunit 3, 60kDa

NCBI Organism

Homo sapiens

Other Product Names

SF3A3, PRP9, PRPF9, SAP61, SF3a60

Tested Applications

WB

Physical Properties

Liquid

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