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USH1C Antibody

Product Specifications

Background

This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

564412

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of zebrafish USH1C (NP_001035018.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Neuroscience

Purification

Affinity purification

Positive Control

HT-29

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 73kDa

Fragment

IgG

Symbol

USH1C

Positive Control 2

Mouse kidney

Positive Control 3

Mouse small intestine

Positive Control 4

Rat testis

Positive Control 5

Rat kidney

NCBI Official Name

Usher syndrome 1C

NCBI Organism

Danio rerio

Other Product Names

Zgc:136806, harmonin, Usher syndrome 1C (autosomal recessive, severe), harmonin pseudogene

Tested Applications

WB, IHC

Physical Properties

Liquid

Curated Selection

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