P4HA2 Antibody

Product Specifications

Background

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

NCBI Gene ID

8974

Swiss Prot

O15460

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 234-533 of human P4HA2 (NP_001136070.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

SKOV3

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 65kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

P4HA2

Positive Control 2

Mouse brain

Positive Control 3

Rat brain

NCBI Official Name

Prolyl 4-hydroxylase subunit alpha 2

NCBI Organism

Homo sapiens

Other Product Names

MYP25, prolyl 4-hydroxylase subunit alpha-2, 4-PH alpha 2, C-P4Halpha (II), collagen prolyl 4-hydroxylase alpha (II), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2, prolyl 4-hydroxylase, alpha polypeptide II