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GAN Antibody

Product Specifications

Background

This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN) .

NCBI Gene ID

8139

Swiss Prot

Q9H2C0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human GAN (NP_071324.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

SW480

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 71kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GAN

Positive Control 2

Mouse skeletal muscle

NCBI Official Name

Gigaxonin

NCBI Organism

Homo sapiens

Other Product Names

GAN1, KLHL16, gigaxonin, epididymis secretory sperm binding protein, kelch-like family member 16, kelch-like protein 16

Tested Applications

WB

Physical Properties

Liquid

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