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STAM Antibody

Product Specifications

Background

This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.

NCBI Gene ID

8027

Swiss Prot

Q92783

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human STAM (NP_003464.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Symbol

STAM

Positive Control 2

Jurkat

Positive Control 3

HeLa

Positive Control 4

HepG2

Positive Control 5

Mouse pancreas

Positive Control 6

Rat liver

NCBI Official Name

Signal transducing adapter molecule 1

NCBI Organism

Homo sapiens

Other Product Names

Signal transducing adapter molecule 1, STAM-1, STAM, STAM1

Tested Applications

WB, IHC

Physical Properties

Liquid

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