S100A6 Antibody, KO Validated
Product Specifications
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
NCBI Gene ID
6277
Swiss Prot
P06703
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human S100A6 (NP_055439.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Cell Cycle, Growth Factors
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 10kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
S100A6
Positive Control 2
NIH/3T3
Positive Control 3
HT-29
Positive Control 4
Mouse lung
Positive Control 5
Mouse skeletal muscle
NCBI Official Name
S100 calcium binding protein A6
NCBI Organism
Homo sapiens
Other Product Names
S100A6, 2A9, 5B10, CABP, CACY, PRA, MLN 4, Protein S100-A6, Calcyclin
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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