RFC3 Antibody
Product Specifications
Background
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.
NCBI Gene ID
5983
Swiss Prot
P40938
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human RFC3 (NP_002906.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
MCF-7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 41kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
RFC3
Positive Control 2
SW480
Positive Control 3
HL-60
Positive Control 4
NIH/3T3
Positive Control 5
293T
Positive Control 6
Mouse liver
NCBI Official Name
Replication factor C (activator 1) 3, 38kDa
NCBI Organism
Homo sapiens
Other Product Names
RFC3, MGC5276, RFC38
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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