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PSMB6 Antibody

Product Specifications

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

NCBI Gene ID

5694

Swiss Prot

P28072

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 35-239 of human PSMB6 (NP_002789.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

HT-29

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 23kDa

Fragment

IgG

Symbol

PSMB6

Positive Control 2

HeLa

Positive Control 3

HepG2

Positive Control 4

MCF7

NCBI Official Name

Proteasome subunit beta 6

NCBI Organism

Homo sapiens

Other Product Names

DELTA, LMPY, Y, proteasome subunit beta type-6, PSY large multifunctional protease Y, macropain delta chain, multicatalytic endopeptidase complex delta chain, proteasome (prosome, macropain) subunit, beta type, 6, proteasome catalytic subunit 1, proteasome delta chain, proteasome subunit Y, proteasome subunit delta

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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