PMM2 Antibody
Product Specifications
Background
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.
NCBI Gene ID
5373
Swiss Prot
O15305
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PMM2 (NP_000294.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 28kDa
Fragment
IgG
Symbol
PMM2
Positive Control 2
A-549
Positive Control 3
HeLa
Positive Control 4
293T
Positive Control 5
NIH/3T3
Positive Control 6
Mouse liver
NCBI Official Name
Phosphomannomutase 2
NCBI Organism
Homo sapiens
Other Product Names
Phosphomannomutase 2, PMM 2, PMM2
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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