PDK2 Antibody
Product Specifications
Background
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
5164
Swiss Prot
Q15119
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 128-407 of human PDK2 (NP_002602.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 46kDa
Fragment
IgG
Symbol
PDK2
Positive Control 2
BT-474
Positive Control 3
HepG2
Positive Control 4
293T
NCBI Official Name
Pyruvate dehydrogenase kinase, isozyme 2
NCBI Organism
Homo sapiens
Other Product Names
PDK2, PDHK2, PDKII
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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