GALC Antibody
Product Specifications
Background
This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI Gene ID
2581
Swiss Prot
P54803
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GALC (NP_000144.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
DU145
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 77kDa
Fragment
IgG
Symbol
GALC
Positive Control 2
293T
Positive Control 3
HepG2
Positive Control 4
A375
Positive Control 5
Mouse brain
Positive Control 6
Rat testis
NCBI Official Name
Galactosylceramidase
NCBI Organism
Homo sapiens
Other Product Names
GALC
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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