FMO2 Antibody

Product Specifications

Background

This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

2327

Swiss Prot

Q99518

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 210-470 of human FMO2 (NP_001451.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 70kDa

Fragment

IgG

Applications Notes

WB: 1:200 - 1:2000

Symbol

FMO2

Positive Control 2

293T

NCBI Official Name

Flavin containing dimethylaniline monoxygenase 2

NCBI Organism

Homo sapiens

Other Product Names

FMO1B1, dimethylaniline monooxygenase [N-oxide-forming] 2, FMO, pulmonary, dimethylaniline oxidase 2, flavin containing monooxygenase 2 (non-functional), pulmonary flavin-containing monooxygenase 2