CPOX Antibody
Product Specifications
Background
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP) .
NCBI Gene ID
1371
Swiss Prot
P36551
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 111-454 of human CPOX (NP_000088.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Symbol
CPOX
Positive Control 2
A375
Positive Control 3
HepG2
Positive Control 4
A-549
Positive Control 5
Mouse liver
Positive Control 6
Rat liver
NCBI Official Name
Coproporphyrinogen oxidase
NCBI Organism
Homo sapiens
Other Product Names
COX, CPO, CPX, HCP, oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial, coprogen oxidase, coproporphyrinogenase
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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