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CPOX Antibody

Product Specifications

Background

The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP) .

NCBI Gene ID

1371

Swiss Prot

P36551

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 111-454 of human CPOX (NP_000088.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 36kDa

Fragment

IgG

Symbol

CPOX

Positive Control 2

A375

Positive Control 3

HepG2

Positive Control 4

A-549

Positive Control 5

Mouse liver

Positive Control 6

Rat liver

NCBI Official Name

Coproporphyrinogen oxidase

NCBI Organism

Homo sapiens

Other Product Names

COX, CPO, CPX, HCP, oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial, coprogen oxidase, coproporphyrinogenase

Tested Applications

WB, IHC

Physical Properties

Liquid

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