ATP6V1B2 Antibody
Product Specifications
Background
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
NCBI Gene ID
526
Swiss Prot
P21281
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 262-511 of human ATP6V1B2 (NP_001684.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Symbol
ATP6V1B2
Positive Control 2
SW620
Positive Control 3
293T
Positive Control 4
U-251MG
Positive Control 5
Mouse kidney
Positive Control 6
Mouse brain
NCBI Official Name
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
NCBI Organism
Homo sapiens
Other Product Names
ATP6V1B2, ATP6B1B2, ATP6B2, V-ATPase subunit B 2, Vma2, VATB, VPP3, HO57, V-ATPase B2 subunit
Tested Applications
WB, IF
Physical Properties
Liquid
Frequently Asked Questions
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