AMFR Antibody
Product Specifications
Background
This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.
NCBI Gene ID
267
Swiss Prot
Q9UKV5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 384-643 of human AMFR (NP_001135.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
SKOV3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 72kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
AMFR
Positive Control 2
DU145
NCBI Official Name
Autocrine motility factor receptor, E3 ubiquitin protein ligase
NCBI Organism
Homo sapiens
Other Product Names
AMFR, GP78, RNF45
Tested Applications
WB
Physical Properties
Liquid
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