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ACO2 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.

NCBI Gene ID

50

Swiss Prot

Q99798

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 501-780 of human ACO2 (NP_001089.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-131

Calculated Molecular Weight

Observed: 105kDa

Fragment

IgG

Symbol

ACO2

Positive Control 2

U-87MG

Positive Control 3

K-562

Positive Control 4

NIH/3T3

Positive Control 5

Mouse brain

Positive Control 6

Rat spinal cord

NCBI Official Name

Aconitase 2, mitochondrial

NCBI Organism

Homo sapiens

Other Product Names

ACO2, ACONM, MGC20605, MGC33908, ICRD

Tested Applications

WB, IF

Physical Properties

Liquid

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