ACO2 Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.
NCBI Gene ID
50
Swiss Prot
Q99798
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 501-780 of human ACO2 (NP_001089.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-131
Calculated Molecular Weight
Observed: 105kDa
Fragment
IgG
Symbol
ACO2
Positive Control 2
U-87MG
Positive Control 3
K-562
Positive Control 4
NIH/3T3
Positive Control 5
Mouse brain
Positive Control 6
Rat spinal cord
NCBI Official Name
Aconitase 2, mitochondrial
NCBI Organism
Homo sapiens
Other Product Names
ACO2, ACONM, MGC20605, MGC33908, ICRD
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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