CIT Antibody

Product Specifications

Background

This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

11113

Swiss Prot

O14578

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1300 of human CIT (NP_001193928.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Chemokines & Cytokines, Immunology, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 231kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CIT

Positive Control 2

HeLa

Positive Control 3

Jurkat

Positive Control 4

Mouse testis

Positive Control 5

Mouse thymus

Positive Control 6

Mouse kidney

NCBI Official Name

Citron rho-interacting serine/threonine kinase

NCBI Organism

Homo sapiens

Other Product Names

CITK, CRIK, MCPH17, STK21, citron Rho-interacting kinase, citron (rho-interacting, serine/threonine kinase 21), serine/threonine kinase 21, serine/threonine-protein kinase 21