TNFRSF4 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
NCBI Gene ID
7293
Swiss Prot
P43489
Host
Rabbit
Reactivity
Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TNFRSF4 (NP_003318.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell
Purification
Affinity purification
Positive Control
Rat liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-120
Calculated Molecular Weight
Observed: 48kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TNFRSF4
NCBI Official Name
TNF receptor superfamily member 4
NCBI Organism
Homo sapiens
Other Product Names
ACT35, CD134, IMD16, OX4TXGP1L, tumor necrosis factor receptor superfamily member 4, ACT35 antigen, ATC35 antigen, CD134 antigen, OX40 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, lymphoid activation antigene ACT35, tax-transcriptionally activated glycoprotein 1 receptor
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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