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AMPD1 Antibody

Product Specifications

Background

Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

NCBI Gene ID

270

Swiss Prot

P23109

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human AMPD1 (NP_001166097.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

A375

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-094

Calculated Molecular Weight

Observed: 80kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

AMPD1

Positive Control 2

SKOV3

Positive Control 3

A-549

Positive Control 4

Mouse heart

Positive Control 5

Mouse lung

Positive Control 6

Rat skeletal muscle

NCBI Official Name

Adenosine monophosphate deaminase 1

NCBI Organism

Homo sapiens

Other Product Names

AMPD1, adenosine monophosphate deaminase 1 (isoform M), MAD, MADA, Adenosine monophosphate deaminase-1 (muscle), OTTHUMP00000059283, MMDD

Tested Applications

WB

Physical Properties

Liquid

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