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NSUN2 Antibody

Product Specifications

Background

This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA (Leu) (CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

NCBI Gene ID

54888

Swiss Prot

Q08J23

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 508-767 of human NSUN2 (NP_060225.4) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 105kDa

Fragment

IgG

Symbol

NSUN2

Positive Control 2

Mouse liver

Positive Control 3

Mouse heart

NCBI Official Name

NOP2/Sun RNA methyltransferase family, member 2

NCBI Organism

Homo sapiens

Other Product Names

NSUN2, FLJ20303, MISU, SAKI, TRM4, MRT5

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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