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PZP Antibody

Product Specifications

Background

The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.

NCBI Gene ID

5858

Swiss Prot

P20742

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 620-740 of human PZP (NP_002855.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Innate Immunity, Neuroscience

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=19-035

Calculated Molecular Weight

Observed: 164kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PZP

Positive Control 2

Mouse liver

Positive Control 3

Rat liver

NCBI Official Name

PZP alpha-2-macroglobulin like

NCBI Organism

Homo sapiens

Other Product Names

CPAMD6, pregnancy zone protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6, Pregnancy zone protein, pregnancy-zone protein

Tested Applications

WB

Physical Properties

Liquid

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