ALDH6A1 Antibody
Product Specifications
Background
This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
4329
Swiss Prot
Q02252
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 326-535 of human ALDH6A1 (NP_005580.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-030
Calculated Molecular Weight
Observed: 58kDa
Fragment
IgG
Symbol
ALDH6A1
Positive Control 2
A-431
Positive Control 3
SH-SY5Y
Positive Control 4
22Rv1
Positive Control 5
MCF7
Positive Control 6
Mouse liver
NCBI Official Name
Aldehyde dehydrogenase 6 family, member A1
NCBI Organism
Homo sapiens
Other Product Names
ALDH6A1, MMSDH, MMSADHA, mitochondrial acylating methylmalonate-semialdehyde dehydrogenase, MGC40271, aldehyde dehydrogenase 6A1, aldehyde dehydrogenase 6 family, member A1
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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