ALDH6A1 Antibody

Product Specifications

Background

This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.

NCBI Gene ID

4329

Swiss Prot

Q02252

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 326-535 of human ALDH6A1 (NP_005580.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 58kDa

Fragment

IgG

Symbol

ALDH6A1

Positive Control 2

A-431

Positive Control 3

SH-SY5Y

Positive Control 4

22Rv1

Positive Control 5

MCF7

Positive Control 6

Mouse liver

NCBI Official Name

Aldehyde dehydrogenase 6 family, member A1

NCBI Organism

Homo sapiens

Other Product Names

ALDH6A1, MMSDH, MMSADHA, mitochondrial acylating methylmalonate-semialdehyde dehydrogenase, MGC40271, aldehyde dehydrogenase 6A1, aldehyde dehydrogenase 6 family, member A1