SUV39H1 Antibody
Product Specifications
Background
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
6839
Swiss Prot
O43463
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SUV39H1 (NP_003164.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
B cells
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 48kDa
Fragment
IgG
Symbol
SUV39H1
Positive Control 2
U-87MG
NCBI Official Name
Suppressor of variegation 3-9 homolog 1 (Drosophila)
NCBI Organism
Homo sapiens
Other Product Names
SUV39H1, KMT1A, MG44, SUV39H, H3-K9-HMTase 1
Tested Applications
WB, IHC, IF, ChIP
Physical Properties
Liquid
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