SOS1 Antibody
Product Specifications
Background
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.
NCBI Gene ID
6654
Swiss Prot
Q07889
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1034-1333 of human SOS1 (NP_005624.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 175kDa/200kDa
Fragment
IgG
Symbol
SOS1
Positive Control 2
Mouse liver
Positive Control 3
Rat brain
Positive Control 4
Rat liver
NCBI Official Name
Son of sevenless homolog 1
NCBI Organism
Homo sapiens
Other Product Names
Son of sevenless homolog 1, SOS-1, SOS1
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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