UFD1L Antibody
Product Specifications
Background
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
NCBI Gene ID
7353
Swiss Prot
Q92890
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human UFD1L (NP_005650.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=19-009
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Symbol
UFD1L
Positive Control 2
A-431
Positive Control 3
Mouse heart
NCBI Official Name
Ubiquitin recognition factor in ER associated degradation 1
NCBI Organism
Homo sapiens
Other Product Names
UFD1L, ubiquitin recognition factor in ER-associated degradation protein 1, UB fusion protein 1, ubiquitin fusion degradation 1 like, ubiquitin fusion degradation protein 1 homolog
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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