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DNMT3A Antibody

Product Specifications

Background

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

NCBI Gene ID

1788

Swiss Prot

Q9Y6K1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DNMT3A

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

Mouse spleen

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 95kDa

Fragment

IgG

Symbol

DNMT3A

Positive Control 2

Mouse skeletal muscle

NCBI Official Name

DNA (cytosine-5) -methyltransferase 3A

NCBI Organism

Homo sapiens

Other Product Names

DNA (cytosine-5) -methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, MHsaIIIA, DNMT3A

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

Frequently Asked Questions

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