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MonoMethyl-Histone H3-R17 pAb

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

NCBI Gene ID

8356

Swiss Prot

P68431

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

A synthetic mono-methylated peptide corresponding to residues surroundingArg17 of human histone H3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

Methylated

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 17kDa

Fragment

IgG

Symbol

H3R17me1

Positive Control 2

H3 protein

NCBI Official Name

Histone cluster 1, H3d

NCBI Organism

Homo sapiens

Other Product Names

H3/b, H3FB, ERBB, ERBB1, HER1, H3/a, H3/c, H3/d, H3/f, H3/h

Tested Applications

WB, IHC, IF, IP, ChIP, ChIPseq

Physical Properties

Liquid

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